Tetra Bio-Pharma Enters into Co-Development Agreement with MAKScientific

Published: February 28, 2020

Tetra Bio-Pharma Enters into Co-Development Agreement with MAKScientific

Tetra Bio-Pharma Inc., an innovator in cannabinoid-derived drug discovery and development, announced that it has signed a co-development definite agreement with MAKScientific. This agreement provides Tetra with access to novel patented new molecules with CB1 and CB2 agonist or antagonist properties. In the long term, this agreement secures patented new drug candidates for Tetra to develop after Caumz and QIXLEEF receive marketing approval.

MAKScientific is a recognized world leader in endocannabinoid research and drug development.  MAKScientific has developed a pipeline of small molecule drugs that target the cannabinoid receptors (CB1 and CB2) as well as other targets implicated in the endocannabinoid system. Under this agreement, MAKScientific will develop new molecules that will be screened by Tetra for potential efficacy in various indications including cancer, pain and inflammation as well as other potential targets of interest to Tetra.

“This collaboration with MAKScientific provides significant opportunities for Panag Pharma Inc to expand the company’s research to derisk and advance novel lead drug compounds to the clinic. MAKScientific’s founder, Professor Alexandros Makriyannis, is a pioneer in drug development in the cannabinoid space and his ground-breaking work has been instrumental to our understanding of how drugs interact with and modulate the endocannabinoid system,” said Dr. Melanie Kelly, CSO Panag Pharma and Tetra.

“A successful Biopharmaceutical company requires a pipeline of patent protected molecules that can become its next generation therapeutics.  Patent protection is one of the most important aspects to safeguarding the company’s assets and its shareholders investments,” commented Dr. Guy Chamberland, CEO and CRO of Tetra.

Tetra is growing rapidly into a fully vertically integrated pharmaceutical company that through its established agreements and strategic partnership can take a new molecule, developed and patented by MAKScientific, and bring it all the way to commercialization.  Tetra can leverage this co-development agreement by using its current know-how:

  • Leverage solubilization intellectual property from our partnership with Altus Formulation;
  • Develop patent protected inhalation Rx drugs based on Tetra IP;
  • Established supply agreements for GMP grade cannabinoids with several suppliers;
  • Established collaborations with manufacturers capable of synthetic commercial pharmaceutical production;
  • Leverage licensed technology from Vitiprints LLC for clinical trial supply and commercial scale production capacity to meet global demand.
  • Internal core capabilities include research and development, regulatory affairs, pharmaceutical drug and device compliance, clinical trial operations;
  • Initiated the preparation for commercialization of prescription drugs.

“Tetra is set for a strong future moving forward and is clearly shaped into a Biopharmaceutical Company of Rx products based on cannabinoid-based drug discovery and development,” said Dr. Guy Chamberland, CEO and CRO.

MAKScientific is a privately held Boston-based company founded in 2004 on the basis of research by Professor Alexandros Makriyannis in the chemistry and biochemistry of the cannabinoid system. The Company is a leader in cannabinergic compound development with the ability to address major unmet medical needs for selected diseases with a clear competitive advantage over present therapies. Our mission is the discovery, development and commercialization of novel therapeutics that modulate the endocannabinoid system: a key regulator of homeostasis.